The document discloses that GPT-5.5 was assessed for its potential to provide assistance in biological and chemical weapons-relevant domains, received a medium risk rating, and is subject to usage policy restrictions on such content as the primary mitigation mechanism.
This analysis describes what OpenAI's agreement states, permits, or reserves. It does not constitute a legal determination about enforceability. Regulatory applicability and practical outcomes may vary by jurisdiction, enforcement context, and individual circumstances. Read our methodology
The disclosure that GPT-5.5 was evaluated and rated at medium risk in biological and chemical threat domains is operationally significant for regulatory compliance purposes, as these domains are subject to specific legal restrictions in most jurisdictions. The primary mitigation described is usage policy enforcement rather than absolute technical restriction.
Interpretive note: The document does not specify the precise content categories or request patterns that trigger usage policy enforcement in the biological and chemical risk domains, making it difficult to assess the practical scope of the disclosed mitigation.
Under the terms disclosed in this document, GPT-5.5 is subject to usage policy restrictions on biological and chemical weapons-relevant content, with policy enforcement serving as the primary control mechanism. Access to this category of content is not described as subject to an absolute technical block.
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Compare across platforms →"GPT-5.5 was evaluated for potential uplift in biological and chemical threat domains as part of the Preparedness Framework assessment. The model received a medium risk rating in these categories, with mitigations including usage policy restrictions on content related to weapons of mass destruction.Excerpt from OpenAI's GPT-5.5 System Card
1) REGULATORY LANDSCAPE: Biological and chemical threat uplift capabilities engage the Biological Weapons Anti-Terrorism Act and the Chemical Weapons Convention Implementation Act in the US, as well as equivalent biosecurity and chemical security frameworks in …
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The disclosure that GPT-5.5 was evaluated and rated at medium risk in biological and chemical threat domains is operationally significant for regulatory compliance purposes, as these domains are subject to specific legal restrictions in most jurisdictions. The primary mitigation described is usage policy enforcement rather than absolute technical restriction.
Under the terms disclosed in this document, GPT-5.5 is subject to usage policy restrictions on biological and chemical weapons-relevant content, with policy enforcement serving as the primary control mechanism. Access to this category of content is not described as subject to an absolute technical block.
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